17-hydroxy-7alpha-mercapto-3-oxo-17alpha- pregn-4-ene-21-carboxylic acid gamma-lactone acetate
Pronounced "al-DACK-tone", Aldactone is a potassium sparing diuretic. Considered a mild diuretic because of its potassium sparing nature, it is still a diuretic (it actually is a testosterone derivative, and a steroid). It inhibits the production of aldosterone, a hormone produced by your adrenal glands. Aldosterone is the regulator that controls how fast your body excretes calcium, magnesium, sodium, and potassium. This means that if you introduce Aldactone into the system it basically signals the body to release sodium and water, but not potassium.
Aldactone (Spironolactone) is usually prescribed for Hyperaldosteroneism (too much secretion of aldosterone by the adrenal glands), high blood pressure, Hypokalemia (Potassium loss), and sometimes used in emergency situations where flushing the system of toxins is needed (overdose), but this last one is rare since more potent diuretics are usually used instead (lasix, or furosemide). One needs to be careful to NOT take in much potassium while using Aldactone, quite the opposite of other non-potassium sparing diuretics like thiazides and furosemides. Keep your potassium intake very low. Since your body is retaining the potassium you could elevate levels too high, which could cause death (hyperakalemia)!
Aldactone has also been shown to be an anti-androgen, by binding to the androgen receptor sites. This can slow typical gains you would achieve using anabolics, but decrease the risk of the typical androgenic side effects like baldness, acne, and prostate enlargement. So it becomes and issue of weighing the benefit of Aldactone to the slowing down of any potential gains you may be making with steroids. Most users do not use Aldactone for any extended length of time (precontest or post-cycle), so this may not be a super-important issue. Women may find benefit with Aldactone by introducing it into a cycle if virilizing symptoms are occurring. Usually 50-75 mg/day for the remainder of the cycle. This might slow gains, but it's better to be safe than sorry. Side effects can be dizziness (low blood pressure), muscle spasms and cramps, gastrointestinal pain, vomiting, and an irregular heart beat.
Aldactone is typically used pre-contest for 5-10 days. Dosages of 75-150 mg/day are common and produce great results. Keep dosages to the bare minimum to prevent your body from shedding any muscle since this is an androgen binding agent.
If you are using Aldactone as a post-cycle agent to help prevent any androgenic side effects (like with Human Corionic Gonadotropin) or to help shed water weight, dosages will typically be 75 mg/day for 4-6 weeks.